Low-power, low shear action continuous BioReactor equipped with high-efficiency mixing system

■RB Mixing system

In general, mixing is accomplished by using impellers to fluidize liquid. The role of impellers in the RB mixing system is not active mixing. The hint lies in natural flow and rectification action, and tornadoes, which are powerful enough to lift up houses. We wondered what the rectification action and tornado forces would create inside the mixing tank. The RB mixing system consists of an impeller, which generates a swirling flow inside the mixing tank, and radial blades that efficiently exchanges the swirling flow (boundary layer effect) toward the center at the bottom of the mixing tank with a tornado-shaped upward flow, forming a system that creates flow patterns that were unthinkable in conventional mixing. The ”RB” in the name comes from its Radial Blade component. Because the swirling flow is the main flow, the relative velocity difference near the blade is diminished, creating an extremely low shear action and superb uniform cell dispersion inside the culture tank, resulting in efficient mixing for biochemicals, pharmaceuticals, energy generation (water treatment), and other applications.

※Vtip：Blade tip peripheral speed

Conventional
mixing

RB Mixing System

High depth,
high circulation formation

Flow action (upper)
/shear stress (lower)